I saw an extended trailer for 50/50 at the Summit booth at Comic Con recently and, other than looking like a really solid script, I defy you to not love this cast.
Catch the premiere at the Toronto International Film Festival in six weeks:50/50
Jonathan Levine, USA
World Premiere
Inspired by personal experiences, 50/50 is a funny, touching and original story of friendship, love, and survival starring Joseph Gordon-Levitt, Seth Rogen, Anna Kendrick, Bryce Dallas Howard and Anjelica Huston.

From Box Office Mojo:

Anna Kendrick smiled big yesterday when she arrived at the airport in Vancouver to get back to work on Seth Rogen’s cancer comedy alongside Joseph Gordon-Levitt.

Anna Kendrick is named by Paper Mag.com as one of its Beautiful People of 2010. The list is not compiled due to a person’s looks or popularity but for his/hers impact in the past year. Here is what they have to say about her: